Eagles middle linebacker Omar Gaither, as reported here, has a Lisfranc sprain in his right foot that Andy Reid said will “most likely” end his season.

Reid said Wednesday that newly acquired linebacker Will Witherspoon would start in the middle when the Eagles oppose the Washington Redskins Monday night at FedEx Field.

Witherspoon, obtained from the Rams for rookie receiver Brandon Gibson and a fifth-round pick, also will play a little weak side linebacker. 

Veteran Jeremiah Trotter and possibly Joe Mays could get snaps in the middle, as well, according to Reid.

Gaither injured the foot late in the 13-9 loss to the Oakland Raiders this past Sunday. He exited the locker room in considerable pain. This could be the end of his career with the Eagles as his contract expires after this season.

Also on the injury front, wide receiver Kevin Curtis, as reported here, will have another doctor evaluate the knee that’s been swelling up on him the past month. Curtis has been frustrated trying to work through the pain.

“MRI’s don’t always tell everything,” Reid said. “He’ll get a second opinion and we’ll go from there.”

Defensive end Victor (knee sprain) and cornerback Dimitri Patterson (strained quadriceps) likely are out this week according Reid.

The good news is left offensive tackle Jason Peters (knee, ankle) was at the walkthrough Thursday morning and is slated to practice, as is guard Todd Herremans, who has missed all five games with a stress fracture in his left foot.

“I think it’s good for him and it’s good for our team,” quarterback Donovan McNabb said. “We’ve kind of just talked about getting out and getting back to old form. He’s excited about it and I think it will help our O-line.”

Reid said Herremans would work at both guard and tackle.

The Big Guy expects a gut check as the Eagles (3-2) face the roughest stretch of their schedule to date. After the Redskins (2-3), who look every bit as desperate as the Raiders, the Birds take on the NFC East-leading Giants (5-1).